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KMID : 1159320210230030283
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Korean Journal of Vision Science
2021 Volume.23 No. 3 p.283 ~ p.293
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Analysis of Factors Influencing Ocular Higher-order Aberrations after Laser-Assisted in Situ Keratomileusis
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Kim Jeong-Mee
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Abstract
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Purpose : To evaluate the factors affecting ocular higher-order aberrations (HOAs) after laser-assisted in situ keratomileusis (LASIK).
Methods : Forty-two eyes of 21 subjects (23.43±2.06 years) who underwent conventional LASIK were enrolled. Ocular HOAs measured using Wavefront Analyzer. The contribution of all independent variables to the HOAs in LASIK subjects was assessed using univariate and multivariate regression analyses. Backward Stepwise multiple regression analysis was used to assess the factors affecting the HOAs in LASIK subjects.
Results : In LASIK subjects, the RMS values of total HOAs were 0.121±0.050 for a 4 mm pupil and 0.570±0.260 for a 6 mm pupil. In multivariate analyses, the Optical zone and OSI were associated with HOAs for a 4 mm pupil size, Corneal thickness, Ablation depth, Optical zone, LCVA (photopic), HCVA (mesopic), and MTF cutoff were associated with HOAs for a 6 mm pupil size. In final multiple regression model, OSI (p=0.036) was significantly associated with HOAs for a 4 mm pupil, Ablation depth (p=0.016), HCVA (mesopic) (p=0.002), and MTF cutoff (p=0.039) were significantly associated with HOAs for a 6 mm pupil.
Conclusion : The findings of this study suggest that the increased HOAs due to the altered cornea after LASIK may affect the visual quality while affecting the optical system of the eye.
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KEYWORD
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Ablation depth, LASIK, Total Higher-order aberrations
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